Acnecide Gel

Acnecide gel is a leave-on topical treatment containing 5% benzoyl peroxide, used to treat mild to moderate acne on the face, chest, and back. It works in three ways — it kills the bacteria that cause acne (killing up to 95% of spot-causing bacteria), unclogs blocked pores by breaking down dead skin cells, and reduces inflammation to help calm redness and swollen spots. It is suitable for adults and young people aged 12 and over. Unlike some acne treatments, Acnecide gel is available without a prescription from pharmacies and can also be ordered through Access Doctor.

Start by washing the affected area with a mild cleanser and gently pat dry. Apply a thin layer of Acnecide gel to the affected area — avoid the eyes, mouth, nostrils, and neck. When you first start using it, apply once a day before bed to allow your skin to build tolerance. If your skin copes well after a few days with only mild redness or peeling, you can increase to twice a day — morning and evening. If irritation increases, drop back to once daily. Never apply more than a thin layer — using extra gel will not clear spots faster but will increase the risk of irritation.

Acnecide typically starts to show results within 4 weeks of regular use, with the full effect usually seen after 8 to 12 weeks. It's important to stick with the treatment consistently — the most common reason it doesn't work is stopping too early. If your acne hasn't improved after 12 weeks of regular use, speak to your pharmacist or one of our clinicians at Access Doctor, who can advise on alternative or combination treatments.

Yes — this is one of the most important practical points to be aware of with Acnecide gel. Benzoyl peroxide can bleach or discolour hair, clothing, towels, and bed linen if it comes into contact with them. To minimise the risk, wash your hands thoroughly after applying the gel, allow it to dry fully before dressing, and consider using white or old towels and pillowcases while using the treatment. Applying the gel in the evening before bed can also help reduce the risk of accidental contact with clothing during the day.

Some degree of skin reaction is very common when you first start using Acnecide, particularly in the first week or two. The most commonly reported side effects are mild burning or stinging, redness, dryness, and skin peeling at the application site — these usually settle as your skin adjusts to the treatment. In rare cases, swelling or blistering can occur — if this happens, stop using the gel and speak to your doctor. A severe allergic reaction is very rare but possible — symptoms include significant swelling of the face or throat, breathing difficulties, or a widespread rash. If any of these occur, call 999 or go to your nearest A&E immediately.

Be cautious about combining Acnecide with other acne treatments or active skincare products. Avoid using it alongside other products that have drying, peeling, or exfoliating effects — such as AHAs, BHAs, retinol, or other benzoyl peroxide products — as this can significantly increase skin irritation. If your clinician has prescribed a combination of topical treatments, apply one in the morning and one in the evening to reduce the risk of irritation. It's fine to use a gentle, non-medicated moisturiser and sunscreen alongside Acnecide.

Yes — benzoyl peroxide can increase your skin's sensitivity to sunlight, making it more prone to burning. Try to avoid prolonged sun exposure while using Acnecide, and always apply an oil-free sunscreen with at least SPF 30 when going outdoors. Avoid using sunbeds altogether during treatment. Applying Acnecide in the evening can help reduce daytime sun sensitivity.

Acnecide is not recommended during pregnancy or breastfeeding, as the safety of benzoyl peroxide during these times has not been fully established. If you are pregnant, planning a pregnancy, or breastfeeding and need acne treatment, speak to your GP before using any acne medication — they can advise on the safest options available to you.