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Foundayo (orforglipron) is a once-daily prescription tablet made by Eli Lilly, licensed in the UK for weight management in adults with a BMI of 30 or above, or 27 or above with a weight-related condition. Unlike Wegovy tablets, it can be taken at any time of day, with or without food.
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18 years +
Max per order
1 pack
Consultation
Yes. A consultation and an independent check of your weight, by video consultation and/or from your GP records, are needed. Licensed for adults with a BMI of 30 or above, or 27 or above with a weight-related condition. Not sure of your BMI? Use our BMI calculator.
Foundayo is the brand name for orforglipron, a once-daily tablet made by Eli Lilly. The MHRA authorised it on 10 August 2026, making the UK the first country in Europe to approve it for weight management and type 2 diabetes. For a fuller introduction, see what Foundayo (orforglipron) is.
It belongs to the GLP-1 receptor agonist family, the same broad group as Wegovy and Mounjaro. It acts on areas of the brain involved in appetite and fullness and slows how quickly the stomach empties, so many people feel full sooner and less hungry between meals. It is licensed to be used alongside a reduced-calorie diet and more physical activity, not instead of them.
What makes Foundayo different is its chemistry. Wegovy and Mounjaro are peptides, which the stomach breaks down, so Wegovy tablets need an empty stomach and Mounjaro is injected. Orforglipron is a small molecule instead, so it can be taken as an ordinary tablet at any time of day, with or without food, and with no wait before eating or drinking. See how it compares with the Wegovy pill and Mounjaro.
Foundayo is a prescription-only medicine. It is not currently available on the NHS; NICE guidance on orforglipron for overweight and obesity is expected on 18 November 2026. At Access Doctor it is prescribed after an online consultation with a GPhC-registered pharmacist independent prescriber, who checks your weight by video consultation and/or from your GP records, part of our weight loss treatment service.
| Active ingredient | Orforglipron |
| Brand name | Foundayo |
| Manufacturer | Eli Lilly |
| Medicine class | GLP-1 receptor agonist (non-peptide) |
| How it is taken | One tablet once daily, any time of day |
| Food restrictions | None |
| Licensed for | Weight management and type 2 diabetes blood sugar control |
| Eligibility | BMI 30 or above, or 27 or above with a weight-related condition |
| UK authorisation | MHRA, 10 August 2026 |
| NHS availability | Not currently available; NICE guidance expected 18 November 2026 |
| Prescription status | Prescription-only medicine (POM) |
Foundayo (orforglipron) is a prescription-only, once-daily tablet licensed in the UK for two indications: weight management in adults, and improving blood sugar control in adults with type 2 diabetes.
For weight management, Foundayo is licensed for adults with a BMI of 30 kg/m2 or above (obesity), or a BMI of 27 kg/m2 or above (overweight) in the presence of at least one weight-related health condition such as type 2 diabetes, high blood pressure, raised cholesterol, obstructive sleep apnoea or cardiovascular disease. It is used as an adjunct to a reduced-calorie diet and increased physical activity, not as a replacement for them.
Foundayo is made by Eli Lilly and was authorised by the MHRA on 10 August 2026, making the United Kingdom the first country in Europe to approve it for weight management and type 2 diabetes. It is the first non-peptide GLP-1 receptor agonist authorised here, and that difference in chemistry is what allows it to be taken as an ordinary tablet with no food restrictions.
Foundayo is not currently available on the NHS. NICE guidance on orforglipron for managing overweight and obesity is expected on 18 November 2026. Until then it is available privately, on prescription, after a clinical consultation. For prices, see how much Foundayo costs in the UK.
Foundayo is a tablet taken once a day at any time, with or without food. Wegovy is available as a weekly injection or a daily tablet that must be taken on an empty stomach, and Mounjaro is a weekly injection. They work on related appetite pathways. Compare Foundayo vs the Wegovy pill and Foundayo vs Mounjaro.
No. That requirement applies to oral semaglutide, not to Foundayo. You can take Foundayo at any time of day, with or without food, and eat and drink normally afterwards.
Not currently. NICE guidance on orforglipron for overweight and obesity is expected on 18 November 2026, and any NHS availability would follow from that. Until then it is available on private prescription.
Adults with a BMI of 30 or above, or 27 or above with a weight-related condition such as type 2 diabetes, high blood pressure or high cholesterol. A prescriber assesses your suitability, including an independent check of your weight by video consultation and/or from your GP records, before anything is prescribed. Check your BMI with our BMI calculator.
Nausea, constipation, diarrhoea, vomiting, indigestion and stomach pain. They are usually most noticeable after starting or increasing the dose and often ease as your body adjusts. See Foundayo side effects.
Obesity is a long-term condition, and appetite signals return to their previous pattern when GLP-1 treatment stops. Your prescriber will discuss how long treatment is likely to continue and what happens afterwards.
Yes, it may make the pill less effective. Use a non-oral method, such as a coil or implant, or add condoms, for 30 days after starting and for 30 days after each dose increase. Stop Foundayo at least 3 weeks before trying to become pregnant.
It starts at 0.8mg once a day and increases at least monthly to 2.5mg and then 5.5mg. If needed, the dose can go up to 9mg, 14.5mg or 17.2mg, the maximum. See the Foundayo dosage guide.
The price depends on your dose and is shown before you pay, with the consultation included. Higher doses usually cost more. See how much Foundayo costs in the UK.
Take it as soon as you can, but never more than one tablet in a day. If you have missed several doses, ask your prescriber before restarting.
Possibly, but there is no direct dose conversion, so your prescriber will decide your starting dose and timing based on your current treatment. Tell them exactly what you take and when you last took it.
Helpful articles and clinical guides related to this treatment category.
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