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Ispaghula fibre and mebeverine in one sachet: fibre to regulate bowel habit, and an antispasmodic to ease cramps and bloating. For adults with IBS diagnosed by a doctor, after an online consultation with a GPhC-registered pharmacist.
For adults with IBS diagnosed by a doctor. Not for phenylketonuria, swallowing problems, a blocked bowel, or a change in bowel habit lasting over 2 weeks. Always take with plenty of water.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 years and over
Max per order
Up to 3 months
Consultation
Yes, online consultation
Fybogel Mebeverine combines ispaghula husk, a soluble fibre that softens and bulks up stools, with mebeverine, an antispasmodic that relaxes the gut muscle. It suits people whose IBS involves both cramps and irregular bowel habit. Our guide to fibre and IBS explains why soluble fibre helps.
If you only need the antispasmodic, mebeverine tablets cost less per day. See mebeverine vs Buscopan vs alverine and all our IBS treatments.
| Active ingredients | Ispaghula husk 3.5g and mebeverine hydrochloride 135mg per sachet |
| Dose | 1 sachet morning and evening, 30 minutes before meals; a third at midday if needed |
| Contains | Aspartame (phenylalanine), potassium and sodium |
| Legal category | Pharmacy medicine (P); supplied after an online consultation |
| Suitable for | Adults 18+ with IBS diagnosed by a doctor |
| Price | 10 sachets £16.99 · 20 £27.99 · 30 £37.99 |
Who we can supply: adults 18 and over whose IBS has been diagnosed by a doctor. We don’t diagnose IBS online: if you haven’t been diagnosed, please see your GP. If you’re 60 or over, we can supply Fybogel Mebeverine for IBS you’ve had for a while, but new or changed bowel symptoms need your GP.
See your GP first (don’t use this treatment) if you have: - blood in your poo, or black poo; - weight loss you can’t explain, or a lump in your tummy or back passage; - a change in your bowel habit and you’re 60 or over; - tummy swelling or bloating that won’t go away, especially if you’re 50 or over (women); - a high temperature, vomiting, or severe pain that keeps getting worse; - a family history of bowel or ovarian cancer, or of coeliac or inflammatory bowel disease, and new symptoms.
Our guide to IBS red flags explains why these matter.
This service isn’t suitable if you’re pregnant or breastfeeding. Please speak to your GP or midwife.
Don’t take Fybogel Mebeverine if you have: - phenylketonuria (it contains aspartame); - difficulty swallowing, or throat or oesophagus problems; - a blocked or narrowed bowel, or a bowel that isn’t moving (ileus, megacolon); - a change in bowel habit that has lasted more than 2 weeks, rectal bleeding you haven’t had checked, or no bowel movement after taking a laxative.
Tell the prescriber if you have kidney problems or are on a low-potassium or low-sodium diet: each sachet contains potassium and sodium.
The mebeverine can ease cramps within hours to days; the fibre takes 12 to 24 hours to start working on bowel habit. If you’re not better after 2 weeks, see your GP.
The mebeverine in Fybogel Mebeverine eases bloating caused by gut spasm. Fibre itself can cause some extra bloating and wind for the first week or two.
Soluble fibre such as ispaghula can firm up loose stools as well as soften hard ones. For diarrhoea-predominant IBS, see also loperamide and our guide to IBS subtypes.
Plain Fybogel is fibre only. Fybogel Mebeverine adds an antispasmodic for cramps. For constipation without IBS, see our laxatives guide.
Mebeverine tablets with a separate fibre supplement, or another antispasmodic. See our comparison guide.
No. Take the last sachet earlier in the evening, with plenty of water.
We don’t supply IBS medicines online in pregnancy or breastfeeding. Please speak to your GP or midwife.
Helpful articles and clinical guides related to this treatment category.
Free consultation
Online review by a UK prescriber
Next-day delivery
Order before 3pm where offered
Discreet packaging
Plain outer packaging