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The original brand of fluconazole: a single capsule that treats vaginal thrush from the inside. For women aged 18 to 60, after an online consultation with a GPhC-registered pharmacist prescriber.
For women aged 18 to 60 with the usual symptoms of thrush. Not for pregnancy, or if you’ve had thrush 4 or more times in a year, and not supplied online if you’re breastfeeding. Tell us every medicine you take.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 to 60 years (women)
Max per order
1 capsule (2 if the prescriber advises a repeat dose)
Consultation
Yes, online consultation
Diflucan is the original brand of fluconazole, made by Pfizer. A single 150mg capsule treats vaginal thrush by stopping the yeast that causes it (Candida) from growing, and it reaches the infection inside the vagina through the bloodstream.
Generic fluconazole contains the same medicine at the same dose and costs less. For itching outside, you can use Canesten Thrush Cream at the same time. See fluconazole vs Canesten and all our thrush treatments.
| Active ingredient | Fluconazole 150mg |
| Brand | Diflucan (Pfizer) |
| Dose | One capsule, once |
| Prescription status | Prescription-only medicine, supplied after an online consultation |
| Suitable for | Women 18 to 60 with vaginal thrush |
| Price | 1 capsule £22.99 · 2 capsules £42.99 |
Who we can supply: women aged 18 to 60 with the usual symptoms of vaginal thrush: itching or soreness, and a thick white discharge that doesn’t smell. It can be your first episode.
This service isn’t suitable if you:
are pregnant, or could be (see your midwife or GP; our thrush in pregnancy guide explains why)
have had thrush 4 or more times in the last 12 months, or twice in the last 6 months (see our recurrent thrush guide)
are under 18 or over 60
have pain in your lower tummy, a high temperature, bleeding that isn’t your period, or blood in the discharge
have a discharge that smells, or is green, yellow or grey (it may be BV or an STI)
have sores, blisters or ulcers around the vagina
have diabetes that isn’t well controlled, or a weakened immune system
We only treat women. Men with genital thrush can get treatment from a pharmacist or GP; see thrush in men.
We don’t supply fluconazole online if you’re breastfeeding (our service rule). We can supply Canesten Thrush Cream for the skin outside; for thrush inside, see your GP or midwife.
Diflucan isn’t suitable if you:
have had an allergic reaction to fluconazole or similar antifungals
have liver or kidney problems, or a heart rhythm problem
take a medicine it interacts with (below)
Tell the prescriber about every medicine you take. Diflucan mustn’t be taken with erythromycin, pimozide, quinidine or cisapride, because together they can cause a dangerous heart rhythm. Clarithromycin and amiodarone need checking for the same reason. It can also increase the effect of warfarin, some statins (such as simvastatin or atorvastatin), some diabetes tablets (such as gliclazide), phenytoin, ciclosporin and others, and it can make clopidogrel work less well.
No. Diflucan comes as capsules and a liquid (and as a drip used in hospital), but not as a cream. For a thrush cream, Canesten Thrush Cream (clotrimazole) soothes itching outside the vagina, and many women use it alongside a Diflucan capsule.
No. They contain the same medicine at the same dose and work equally well. Generic fluconazole costs less; some people prefer the brand they know.
Your symptoms should improve within 7 days of the single capsule. If they haven’t, see your GP or a sexual health clinic.
Fluconazole is licensed for genital thrush in men, but our online service is for women. Men can get treatment from a pharmacist or GP. See thrush in men.
Not with erythromycin, pimozide, quinidine or cisapride, and clarithromycin and amiodarone need checking. It can also increase the effect of warfarin, some statins (such as simvastatin and atorvastatin) and some diabetes tablets, and make clopidogrel work less well. Tell the prescriber everything you take.
We don’t supply Diflucan online if you’re breastfeeding; this is our service rule, not a ban on the medicine. We can supply Canesten Thrush Cream for the skin outside the vagina; for thrush inside, see your GP or midwife.
No. Fluconazole isn’t used in pregnancy. Thrush in pregnancy is usually treated with a clotrimazole pessary; please see your midwife or GP. See thrush in pregnancy.
If you’ve had thrush 4 or more times in a year, or twice in 6 months, please see your GP. They can check it’s thrush, look for causes such as diabetes, and offer a longer course. We don’t supply the 6-month course online. See recurrent thrush.
Helpful articles and clinical guides related to this treatment category.
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