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A single capsule that treats vaginal thrush from the inside. For women aged 18 to 60, after an online consultation with a GPhC-registered pharmacist prescriber.
For women aged 18 to 60 with the usual symptoms of thrush. Not for pregnancy, or if you’ve had thrush 4 or more times in a year, and not supplied online if you’re breastfeeding. Tell us every medicine you take.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 to 60 years (women)
Max per order
1 capsule (2 if the prescriber advises a repeat dose)
Consultation
Yes, online consultation
Fluconazole is an antifungal medicine. A single 150mg capsule treats vaginal thrush by stopping the yeast that causes it (Candida) from growing. It works through the bloodstream, so it reaches the infection inside the vagina. It’s the same medicine as Diflucan, the original brand, at a lower price.
For itching on the skin outside the vagina, you can use Canesten Thrush Cream at the same time. Our guide to fluconazole vs Canesten compares them, and our thrush guide explains the symptoms. See all our thrush treatments.
| Active ingredient | Fluconazole 150mg |
| Type | Antifungal (triazole) |
| Dose | One capsule, once |
| Prescription status | Prescription-only medicine, supplied after an online consultation |
| Suitable for | Women 18 to 60 with vaginal thrush |
| Price | 1 capsule £5.99 · 2 capsules £9.99 |
Who we can supply: women aged 18 to 60 with the usual symptoms of vaginal thrush: itching or soreness, and a thick white discharge that doesn’t smell. It can be your first episode.
This service isn’t suitable if you:
are pregnant, or could be (see your midwife or GP; our thrush in pregnancy guide explains why)
have had thrush 4 or more times in the last 12 months, or twice in the last 6 months (see our recurrent thrush guide)
are under 18 or over 60
have pain in your lower tummy, a high temperature, bleeding that isn’t your period, or blood in the discharge
have a discharge that smells, or is green, yellow or grey (it may be BV or an STI)
have sores, blisters or ulcers around the vagina
have diabetes that isn’t well controlled, or a weakened immune system
We only treat women. Men with genital thrush can get treatment from a pharmacist or GP; see thrush in men.
We don’t supply fluconazole online if you’re breastfeeding (our service rule). We can supply Canesten Thrush Cream for the skin outside; for thrush inside, see your GP or midwife.
Fluconazole isn’t suitable if you:
have had an allergic reaction to fluconazole or similar antifungals
have liver or kidney problems, or a heart rhythm problem
take a medicine it interacts with (below)
Tell the prescriber about every medicine you take. Fluconazole mustn’t be taken with erythromycin, pimozide, quinidine or cisapride, because together they can cause a dangerous heart rhythm. Clarithromycin and amiodarone need checking for the same reason. It can also increase the effect of warfarin, some statins (such as simvastatin or atorvastatin), some diabetes tablets (such as gliclazide), phenytoin, ciclosporin and others, and it can make clopidogrel work less well.
Your symptoms should improve within 7 days of the single capsule. If they haven’t, see your GP or a sexual health clinic, because it may not be thrush.
Yes. Diflucan is the original brand of fluconazole. Both contain 150mg of fluconazole and work in the same way; the generic costs less.
Fluconazole comes as 50mg, 150mg and 200mg capsules, plus a liquid. For vaginal thrush, the standard dose is a single 150mg capsule. The other strengths are used for other fungal infections, such as thrush in the mouth or more serious infections, usually over several days. We only supply the 150mg capsule, for vaginal thrush.
They work as well as each other. Fluconazole is a single capsule that treats the infection inside; Canesten Thrush Cream soothes itching outside. Many women use both. See fluconazole vs Canesten.
Usually, yes, but not with erythromycin, and some other antibiotics need checking. Tell the prescriber everything you take. See thrush after antibiotics.
Alcohol doesn’t interact with a single dose of fluconazole, but it can make side effects such as feeling sick or a headache worse.
We don’t supply fluconazole online if you’re breastfeeding; this is our service rule, not a ban on the medicine. We can supply Canesten Thrush Cream for the skin outside the vagina; for thrush inside, see your GP or midwife.
No. Fluconazole isn’t used in pregnancy. Thrush in pregnancy is usually treated with a clotrimazole pessary; please see your midwife or GP. See thrush in pregnancy.
If you’ve had thrush 4 or more times in a year, or twice in 6 months, please see your GP. They can check it’s thrush, look for causes such as diabetes, and offer a longer course. We don’t supply the 6-month course online. See recurrent thrush.
Helpful articles and clinical guides related to this treatment category.
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Order before 3pm where offered
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