Omeprazole
From £14.99
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Our friendly team is available to help Monday to Friday 9:00am – 5:00pm.
If you need urgent assistance, do not use this service. Call 111, or in an emergency call 999.
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Acid reflux treatment in the UK focuses on reducing stomach acid and relieving symptoms like heartburn and regurgitation. The most effective treatments are proton pump inhibitors (PPIs), including omeprazole and lansoprazole, which provide fast, long-lasting relief from GORD.
Start your acid reflux treatment online with UK-registered prescribers and discreet next-day delivery.
The right acid reflux treatment depends on how often your symptoms occur and how severe they are.
Proton pump inhibitors (PPIs) — most effective treatment
Omeprazole, lansoprazole, esomeprazole and pantoprazole are the most effective treatments for acid reflux and GORD. They reduce stomach acid production and allow the oesophagus to heal.
👉 Most people notice improvement within 1–4 days, with full relief in 1–2 weeks.
Our clinicians may recommend one of the treatment options below, depending on your symptoms, medical history, and whether the treatment is appropriate for you.
| Treatment | How it works | Best for | How quickly it works | Duration of action | Example |
|---|---|---|---|---|---|
| Omeprazole (PPI) | Reduces stomach acid by blocking proton pumps | Frequent or severe acid reflux (GORD) | 1–4 days (full effect 1–2 weeks) | 24 hours+ | Omeprazole 20mg / 40mg |
| Lansoprazole (PPI) | Reduces stomach acid production (similar to omeprazole) | Frequent symptoms or alternative if omeprazole not suitable | 1–4 days (full effect 1–2 weeks) | 24 hours+ | Lansoprazole 15mg / 30mg |
| Esomeprazole (PPI) | More bioavailable PPI for stronger acid suppression | Persistent or severe GORD | 1–4 days (full effect 1–2 weeks) | 24 hours+ | Esomeprazole 20mg / 40mg |
| H2 blockers | Reduce acid via histamine receptors | Mild to moderate symptoms | Within hours | 6–12 hours | Famotidine |
| Alginates | Form a barrier to prevent acid reflux | Occasional heartburn, after meals | Immediate | Up to 4 hours | Gaviscon Advance |
Not sure which option is right for you?
Complete a short consultation so our clinicians can understand your acid reflux treatment online treatment needs.
A prescriber checks whether treatment is clinically safe and appropriate for you.
If approved, your treatment is dispensed and delivered in plain packaging.
Speak to a clinician if your symptoms are persistent, worsening, or affecting your quality of life.
To improve results from your acid reflux treatment:
*Avoid eating before bed
*Raise the head of your bed
*Reduce trigger foods
*Maintain a healthy weight
*Stop smoking
Acid reflux occurs when stomach acid flows back into the oesophagus.
Common causes include:
Large meals or eating late
Fatty or spicy foods
Alcohol and caffeine
Being overweight
Pregnancy
Managing these alongside treatment improves symptom control.
→ Choose Omeprazole Standard first choice for acid reflux treatment Effective for most people Widely prescribed and well tolerated
→ Choose Lansoprazole Similar effectiveness Often used if omeprazole isn’t suitable Alternative first-line option
→ Choose Esomeprazole Stronger acid suppression More effective in resistant symptoms Often used for ongoing or severe reflux
Best starting option: Omeprazole
Alternative option: Lansoprazole
Stronger treatment: Esomeprazole
Still unsure?
Complete a short online consultation and a UK prescriber will recommend the most suitable acid reflux treatment based on your symptoms and medical history.
The best acid reflux treatment in the UK are proton pump inhibitors such as omeprazole or lansoprazole. These are the most effective medications for reducing stomach acid and treating GORD.
Acid reflux treatment usually starts working within 1 to 4 days. Full symptom relief may take up to 2 weeks with regular use. One of our prescribers could help advise you on your suitability. For long term treatment please discuss this with your own general practitioner (GP).
The best medication for heartburn treatment is a PPI such as omeprazole. Alginates such as Gaviscon can also provide fast relief for occasional symptoms.
Acid reflux treatment may not work if it is not taken correctly or if symptoms are more severe. A higher dose or different medication may be needed.
Some acid reflux treatments are available over the counter, but stronger medications usually require a prescription in the UK.
Helpful reads related to this treatment area.
AA Medically authored & reviewed by Dr Abdishakur M Ali GP · Telehealth Ex …
AA Medically authored & reviewed by Dr Abdishakur M Ali GP · Telehealth Ex …
AA Medically authored & reviewed by Dr Abdishakur M Ali GP · Telehealth Ex …
Start a short online consultation and our clinical team will review whether treatment is suitable for you.
