Losec MUPS tablets contain the active ingredient Omeprazole, these are dispersible tablets that works by reducing the amount of acid that your stomach makes.

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What is Losec?

Losec MUPS (Multiple Unit Pellet System) tablets contain the active ingredient Omeprazole. It is a type of medicine called a proton pump inhibitor (PPI). It acts in the stomach to decrease the production of stomach acid. This in turn reduces pain or discomfort in your chest or stomach and allows your body to heal any inflammation in your stomach lining. PPIs are excellent treatment options for acid reflux and indigestion.

Stomach acid inhibitors like Losec MUPS tablets are used to treat stomach problems such as heartburn, acid reflux, bloating and stomach pain. These symptoms can be caused by peptic ulcers, oesophagitis (inflammation of the oesophagus) or Zollinger-Ellison syndrome (excessive secretion of stomach acid due to a tumour or enlargement of the pancreas). Losec MUPS tablets can also be used as a stomach coater to prevent stomach problems that can occur as a side effect of certain drugs.

How to use Losec

Losec MUPS tablets should be swallowed whole, without chewing, with some liquid. People who have difficulty swallowing can disperse the tablets in half a glass of water or juice. The pellets in the mixture should not be chewed. Rinse the glass with half a glass of water and drink this to ensure that no medicine is left behind in the glass. Losec MUPS tablets may be taken with or without food. Try to take the tablets in the morning and at the same time each day. If you are taking Losec MUPS twice daily, do so in the morning and at night. The number of tablets to take and for how long will depend on the condition being treated. It is important to follow the instructions given by your doctor.


Losec MUPS tablets are available in three strengths: 10 mg, 20 mg and 40 mg. Unless otherwise prescribed by a doctor, the usual dose for most stomach conditions is:

Adults: one 20-mg or 40-mg tablet, once a day.

Side effects & precautions

Losec MUPS tablets are not suitable for everyone. This stomach acid inhibitor should not be used if:

  • You are allergic to omeprazole or other proton pump inhibitors;
  • You are allergic to any of the active ingredients in this medicine;
  • You are taking the anti-HIV medicine nelfinavir.

Consult your doctor on the use of this medicine if you have health problems. Be sure to inform the doctor of any medicines and nutritional supplements you are taking. Losec MUPS tablets may interact with certain medicines, so the doctor should check if the combination is safe.

Pregnancy/driving ability/alcohol

Losec MUPS should not be used by pregnant or breastfeeding women without consulting a doctor first. Losec MUPS may cause dizziness or sleepiness, especially during the first days of treatment. Stay out of traffic if you experience these side effects. Alcohol may worsen stomach problems. Drinking alcohol should be avoided while taking this medicine

Medicines can cause side effects, although some people may not experience any. The most commonly reported side effects of Losec MUPS include:

  • Constipation
  • Diarrhoea
  • Wind
  • Feeling sick
  • Sleepiness
  • Vomiting
  • Headaches

Long-term use of PPIs may cause other side effects:

Increased risk of certain gastrointestinal infections e.g. Clostridium difficile

Observational studies show an increased risk of developing osteoporosis (a condition

that affects bones) and bone fractures.

Consult a doctor if the side effects are persistent. For a complete list of possible side effects, see the package leaflet.

Reporting of side effects

If you get any side effects talk to your doctor or pharmacist. This includes any possible side effects listed on the attached leaflet. You can also report side effects directly via the internet at www.mhra.gov.uk/yellowcard. By reporting side effects, you can help provide more information on the safety of this medicine

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