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Losec MUPS is branded omeprazole in a tablet that can be swallowed whole or dispersed in water. Prescribed online by our GPhC-registered pharmacist prescribers if suitable for you.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 years +
Max per order
3 packs
Consultation
Yes - free online
Losec MUPS contains omeprazole, a proton pump inhibitor (PPI) that reduces the amount of acid your stomach makes. It is used to treat acid reflux and heartburn (GORD), stomach and duodenal ulcers, and – with antibiotics – Helicobacter pylori infection.
MUPS stands for Multiple Unit Pellet System: each tablet contains hundreds of tiny coated pellets of omeprazole. The tablet can be swallowed whole or dispersed in water, which can help if you find tablets or capsules hard to swallow.
Losec MUPS is a prescription-only medicine. Your online consultation is reviewed by one of our GPhC-registered pharmacist prescribers, who confirms whether it is suitable for you. Generic omeprazole contains the same active ingredient and usually costs less.
For more on omeprazole, see our omeprazole guide. Always read the patient information leaflet inside the pack.
| Brand | Losec MUPS (branded omeprazole) |
| Active ingredient | Omeprazole |
| Strength | 20mg gastro-resistant dispersible tablets |
| Pack sizes | 28 or 56 tablets |
| Price from | £29.99, including consultation and prescription |
| How to take | Once a day, swallowed whole or dispersed in still water |
| Generic alternative | Omeprazole capsules |
| Legal status | POM — Prescription Only Medicine |
Losec MUPS 20mg tablets cost £29.99 for 28 and £54.99 for 56. Every price includes your online consultation and prescription, with no separate consultation fee.
Both contain omeprazole and work in the same way. Losec is the original brand, and the MUPS tablet can be dispersed in water, which some people find easier than swallowing a capsule. Generic omeprazole capsules usually cost less, and their contents can also be mixed with a drink or apple sauce if needed.
Yes. Losec MUPS is a prescription-only medicine. At Access Doctor you complete an online consultation, and one of our pharmacist prescribers issues a prescription if it is suitable for you.
Take one tablet a day, usually in the morning. Swallow it whole with water, or break it up and disperse it in a spoonful of still (non-fizzy) water – you can mix it with some fruit juice or apple sauce. Do not use milk or fizzy water. Stir, take it within 30 minutes, then rinse the glass with half a glass of water and drink that too. Do not chew or crush the pellets.
Each tiny pellet has its own acid-resistant coating, which protects the omeprazole from stomach acid until it reaches the small intestine. Chewing or crushing the pellets breaks this coating and stops the medicine working properly.
Common side effects include headache, stomach pain, diarrhoea, constipation, wind and feeling sick. Harmless stomach polyps can also develop. Tell your prescriber if you get a rash on sun-exposed skin with joint pain, severe or persistent diarrhoea, or symptoms of low magnesium such as muscle cramps or a fast heartbeat.
Do not take Losec if you are allergic to omeprazole or similar medicines, or if you take the HIV medicines nelfinavir or rilpivirine. It is not recommended with atazanavir. It should be avoided with clopidogrel unless essential – a different PPI is usually used instead. Tell your prescriber if you take warfarin, methotrexate, digoxin, tacrolimus, phenytoin, cilostazol, ketoconazole or itraconazole, or St John's wort.
Omeprazole is the PPI usually recommended in pregnancy and while breastfeeding, as it has been widely used without evidence of harm. Speak to your prescriber or GP first.
Yes, a small amount. Each 20mg tablet contains about 19 to 20mg of sucrose. Do not take it if you have a rare inherited problem with fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency.
Call 999 or go to A&E if you are vomiting blood or have black, tarry stools, or have sudden chest pain that does not go away. See a GP urgently if you have difficulty swallowing, unexplained weight loss or persistent vomiting, or are 55 or over and have lost weight along with indigestion, reflux or upper tummy pain. Also see a GP if your symptoms have not improved after 4 weeks of treatment.
Take ONE a day
Swallow this medicine whole. Do not chew or break.
Helpful articles and clinical guides related to this treatment category.
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