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Priligy (dapoxetine hydrochloride) is a prescription medication that is used to treat Premature Ejaculation (PE). It belongs to a class of drugs called selective serotonin re-uptake inhibitors (SSRI) and is the only drug approved in the UK for the treatment of PE.
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Priligy is a prescription-only medicine and is not widely available on the NHS. Your online consultation with Access Doctor will help determine if Priligy is right for you.
Do not take Priligy if you are under 18 or over 65 years of age.
Do not take Priligy if you have severe heart problems, moderate to severe liver problems, a history of fainting, epilepsy, glaucoma, or bipolar disorder.
Do not take Priligy if you are taking MAOIs, thioridazine, lithium, tramadol, linezolid, St John's wort, or other SSRIs/SNRIs.
Do not drink alcohol while taking Priligy.
Do not drive or operate machinery if you feel dizzy or light-headed after taking Priligy.
If you experience any changes in your mood or suicidal thoughts, stop taking Priligy immediately and contact your doctor.
If you feel faint, dizzy, or light-headed, lie down immediately with your head between your knees until the symptoms pass.
At Access Doctor, you can buy Priligy tablets following a confidential online consultation with a UK-registered clinician. Both branded Priligy and generic dapoxetine (30mg and 60mg) are available options. The Priligy price is competitive, and you can order Priligy online with free, discreet Priligy next day delivery directly to your home. If you are looking for a cost-effective treatment for premature ejaculation, generic dapoxetine provides the same active ingredient as Priligy at a lower price – ask your clinician about the best option for you.
This information is for educational purposes and does not replace the advice of your doctor or pharmacist. Always read the patient information leaflet inside the pack. If you are unsure about any aspect of your treatment, speak to a healthcare professional.
Priligy is a prescription-only medicine that contains the active ingredient dapoxetine (30mg or 60mg per tablet). It is used specifically to treat premature ejaculation (PE) in adult men aged 18 to 64. Premature ejaculation is defined as ejaculating with minimal sexual stimulation, often within two minutes of penetration, and with a persistent lack of control that causes distress. Dapoxetine is the only licensed oral treatment for premature ejaculation in the UK. Unlike daily antidepressant tablets, dapoxetine is a short-acting SSRI taken on demand, designed to be in and out of your system within 24 hours. Before you start treatment, it is important to understand that Priligy does not cure premature ejaculation – it only helps control it when you take it. It also does not address psychological causes such as anxiety, performance pressure, or relationship difficulties. If these are contributing factors, you may benefit from speaking to a therapist or counsellor as well. It is also not a treatment for erectile dysfunction. If you have erection problems alongside premature ejaculation, you should discuss both issues with your doctor.
Priligy works by temporarily raising the levels of a natural chemical in your brain called serotonin. Serotonin plays a key role in controlling how quickly you ejaculate. When you are sexually aroused, signals travel between your brain and your nervous system. In men with premature ejaculation, the serotonin system can be too active, causing the signal to trigger ejaculation too quickly. Dapoxetine works by blocking the reabsorption of serotonin, keeping levels higher for longer. This slows down the ejaculatory reflex, helping you last up to three times longer and giving you better control. Because dapoxetine is a short-acting SSRI, it leaves your system within 24 hours, which means you only need to take it when you plan to have sex, not every day like traditional antidepressants.
Taking Priligy correctly is essential for the best results. The medicine is designed for on-demand use, not continuous daily use. Dosage: The recommended starting dose is one 30mg tablet. Do not take more than one tablet in any 24-hour period. When to take it: Take your tablet 1 to 3 hours before you plan to have sex. For most men, the effect is strongest about one hour after taking it, but it can remain effective for several hours. How to take it: Swallow the tablet whole with at least one full glass of water – this helps to reduce the risk of fainting. You can take it with or without food. Avoid alcohol: You should not drink alcohol when using Priligy, as alcohol increases the risk of dizziness, fainting, and other side effects. Avoid grapefruit juice: Do not drink grapefruit juice within 24 hours before taking Priligy, as it can increase the level of the active ingredient in your body and make side effects more likely. If 30mg is not effective for you and you are not experiencing troublesome side effects, your doctor may increase the dose to 60mg. You should never increase your dose on your own. If you are using Priligy for the first time, prescribers will only supply the 30mg strength. What if you miss a dose? Because Priligy is taken on demand, there is no fixed dosing schedule. If you forgot to take it before sex, you can still take it as long as you are 1–3 hours away from sexual activity. If you are already having sex, it is too late for that occasion – just take it next time. What if you vomit after taking it? If you vomit within one hour of taking the tablet, the medicine may not have been fully absorbed. You should not take another tablet – just try again on another day. If vomiting continues, contact your doctor. How many times can you use it? You can use Priligy every time you have sex, provided you leave at least 24 hours between doses. Do not take more than one dose in a 24-hour period. For most men, using it 1–2 times per week is common, but frequency can vary based on your needs.
The Priligy price depends on the strength, the number of tablets, and where you purchase it. As a branded medicine, Priligy is more expensive than the generic version (dapoxetine), which contains exactly the same active ingredient. If you want to buy Priligy online, it is available through registered UK online pharmacies with a private prescription. If you want to order Priligy online, the process is straightforward. Priligy is a prescription-only medicine, meaning you cannot simply add it to your shopping basket. You must complete a short online consultation – a health questionnaire that asks about your medical history, any other medicines you are taking, and your symptoms. A UK-registered doctor or pharmacist reviews your answers to ensure Priligy is safe and appropriate for you. If approved, they issue a private prescription and your medication is dispatched. The price you see typically covers both the consultation fee and the medication. All regulated online pharmacies are registered with the General Pharmaceutical Council (GPhC). You should never buy Priligy from unregulated websites – counterfeit medicines can contain dangerous substances and will not work. Why is generic dapoxetine cheaper? Generic medicines contain the same active ingredient as the branded version but do not carry the same research, development, and marketing costs. Generic dapoxetine is the most cost-effective way to treat premature ejaculation, costing as little as £18.74 for 3 tablets. If you are looking for a cheaper alternative to Priligy, dapoxetine is the same medicine at a fraction of the price.
Priligy is clinically proven to be highly effective. Key results from studies include: - Increases ejaculation time by at least one minute in 69% of men and up to two minutes in 44% of men. - Helps men last up to three times longer during sex. - Rated as effective in 8 out of 10 men (80%). - After 9 months of treatment, around 70% of men reported "fair," "good," or "very good" control over their ejaculation. Many men experience benefits the first time they try Priligy. However, some men may need to use it a few times before noticing a significant improvement. You should take Priligy for at least 4 weeks (or at least 6 doses) to properly assess whether it is effective for you.
Like all medicines, Priligy can cause side effects, although not everyone gets them. Most side effects are mild and short-lasting. The most common side effects are dizziness, nausea, and headache. Common side effects (may affect up to 1 in 10 men): - Nausea – taking the tablet with a full glass of water can help reduce this. - Dizziness or light‑headedness – if you feel dizzy, stop what you are doing and sit or lie down immediately. Do not drive or operate machinery until you feel better. - Headache - Fatigue (feeling unusually tired) - Insomnia (trouble sleeping) - Anxiety, agitation or restlessness - Blurred vision - Diarrhoea Serious side effects – rare but you need to know about them: Fainting (syncope) – Priligy can cause a drop in blood pressure that may lead to fainting. You may experience warning symptoms such as nausea, dizziness or light‑headedness before you faint. If you feel any of these, immediately lie down or sit down with your head between your knees until the symptoms pass. Drinking a full glass of water when you take the tablet can help reduce this risk. Changes in mood – including thoughts of suicide or harming yourself. If you experience any changes in your mood, suicidal thoughts, or feelings of harming yourself, stop taking Priligy immediately and contact your doctor. Seizures (fits) – stop taking the medicine and seek medical help if you have a seizure. Serotonin syndrome – a rare but serious condition caused by too much serotonin. Symptoms include agitation, confusion, rapid heartbeat, high temperature, muscle rigidity, and sweating. Allergic reaction – swelling of your face, lips, tongue or throat, or difficulty breathing. Seek emergency medical help immediately. When to seek medical help: - If you feel faint, dizzy or light-headed – lie down immediately. - If you experience any changes in your mood or suicidal thoughts – stop treatment and contact your doctor. - If you have a seizure. - If you have an erection that lasts more than 4 hours – this is rare with Priligy but seek emergency help. Driving and operating machinery: Priligy may cause dizziness, drowsiness, blurred vision, and fainting. You should not drive or operate machinery until you know how the medicine affects you. If you feel dizzy or light-headed, do not drive.
There are several groups of men who should not take Priligy. This is very important. Do NOT take Priligy if: - You are under 18 or over 65 years of age – the safety and efficacy of Priligy have not been established in these age groups. - You are allergic to dapoxetine or any of the other ingredients in the tablet. - You have severe heart problems – including heart failure, significant ischaemic heart disease, heart rhythm problems, or significant heart valve disease. - You have moderate or severe liver problems. - You have severe kidney problems. - You have a history of fainting (syncope) or a tendency to faint. - You have been diagnosed with bipolar disorder or have ever had mania (feeling overexcited, irritable, or having racing thoughts). - You have epilepsy or a history of seizures. - You have glaucoma (increased pressure in your eye). - You have a bleeding or clotting disorder. - You are taking MAOIs (monoamine oxidase inhibitors) – you must stop these for at least 14 days before starting Priligy. - You are taking thioridazine (for schizophrenia). - You are taking lithium (for bipolar disorder). - You are taking St John's wort (a herbal remedy for depression) – you must stop this before starting Priligy. - You are taking tramadol (for severe pain). - You are taking linezolid (an antibiotic). - You are taking tryptophan (a sleep aid). - You are taking other SSRIs or SNRIs (antidepressants such as fluoxetine, sertraline, citalopram, duloxetine, venlafaxine) – you must stop these before starting Priligy. Seek medical advice before doing so. If you have any of these conditions or are taking any of these medicines, you may still be able to take Priligy after a washout period, but only under medical supervision.
Yes, Priligy can interact with several other medicines. Some interactions are dangerous, while others require dose adjustments or monitoring. Do NOT take Priligy with the following: - MAOIs – dangerous interaction; need a 14-day washout. - Thioridazine – can cause serious heart rhythm problems. - Lithium – risk of serotonin syndrome. - Tramadol – risk of serotonin syndrome and seizures. - Linezolid – increased risk of serotonin syndrome. - St John's wort – reduces effectiveness and increases risk of side effects. - Other SSRIs or SNRIs – risk of excessive serotonin levels. Interactions that need caution (tell your doctor): Erectile dysfunction medicines – such as sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra), and avanafil (Spedra). Both Priligy and ED medicines can lower blood pressure, so taking them together can increase the risk of fainting, dizziness, and light‑headedness. Some studies have evaluated dapoxetine with PDE5 inhibitors and have found the combination to be generally well tolerated, but caution is still advised. You should discuss this with your doctor before combining treatments. Strong CYP3A4 inhibitors – such as ketoconazole (antifungal), ritonavir (HIV medicine), clarithromycin (antibiotic), itraconazole (antifungal). These can increase dapoxetine levels and the risk of side effects. Alcohol – do not drink alcohol while taking Priligy, as it increases the risk of fainting and drowsiness. Triptans (migraine medicines) – increased risk of serotonin syndrome. If you take ED medication for erectile dysfunction, you should speak to your doctor about the safest way to use Priligy alongside it. You may need to separate the doses or take additional precautions to avoid low blood pressure and fainting. If you have both ED and PE, you may need a combined approach – always follow medical advice.
Priligy is available on the NHS, but with significant restrictions. The NHS Somerset formulary states that it can be prescribed for the treatment of premature ejaculation in men aged 18 to 64 who meet all of the following criteria: poor control over ejaculation, a history of premature ejaculation over the past 6 months, marked distress or interpersonal difficulty as a consequence of premature ejaculation, and a time to ejaculation of less than two minutes. The maximum supply is 6 tablets per month. However, many NHS formularies – including Nottinghamshire, Cambridgeshire and Peterborough, Greater Manchester, and NHS Scotland – list Priligy as "Non Formulary" or "Not Recommended". In these areas, it is considered a self-care treatment that patients should purchase privately. In NHS Scotland, the Scottish Medicines Consortium (SMC) does not recommend dapoxetine for use within NHSScotland. This means that for most men in the UK, the easiest and most accessible way to get Priligy is to order Priligy online through a private prescription from a registered online pharmacy. This route is quick, discreet, and avoids the need for a GP appointment.
If you order Priligy online through a regulated service and complete the consultation before the daily cut-off time (usually mid-afternoon), your order will be dispatched the same day. Most UK online pharmacies offer Priligy next day delivery as a standard service, with orders arriving by Royal Mail Tracked 24 or a similar courier service. Delivery is often free on orders over a certain amount, and the packaging is discreet – plain and unmarked – so no one else knows what is inside. Once dispatched, you will receive tracking information so you can follow your delivery. Some pharmacies also offer click‑and‑collect, allowing you to pick up your order from a local pharmacy branch in as little as two hours after approval. Because you can buy Priligy online through a service that includes a free online consultation and private prescription, it is a convenient and discreet option. The price you see typically covers both the consultation and the medication, with free next day delivery included.
Yes, Priligy can be used alongside delay creams such as EMLA, but you should be cautious and seek medical advice first. EMLA is a topical anaesthetic cream containing lidocaine and prilocaine that works by numbing the penis to reduce sensitivity, while Priligy works internally on your brain chemistry. Because they work in completely different ways, some men find that using both provides an even greater effect. However, you should not combine treatments without discussing it with a doctor or pharmacist. Potential risks include excessive reduction in sensation (making it difficult to maintain an erection) and increased risk of side effects. Do not combine Priligy with EMLA without medical supervision. If you are looking for a topical treatment for PE, alternatives to EMLA include Stud 100 delay spray and thicker condoms. These can be used alongside Priligy, but again, you should seek medical advice first. Priligy has the advantage of being more discreet – you do not need to apply anything to your penis before sex, and there is no risk of the medicine transferring to your partner.
Store below 25°C (room temperature) in a dry place, away from direct sunlight and heat. Keep the blister pack in its outer carton to protect it from moisture. Keep the medicine out of the sight and reach of children. Do not use the tablets after the expiry date printed on the packaging. If you have any leftover tablets, do not throw them away in household waste or pour them down the sink. Take them to your local pharmacy, where they will be disposed of safely.
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