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Cyclizine is an antihistamine medicine used to prevent and treat nausea, vomiting and dizziness. It's commonly recommended for motion sickness, vertigo caused by inner ear problems, and nausea following surgery or radiotherapy. Cyclizine works by calming the balance signals sent from the inner ear to the brain, and by blocking the chemical pathways in the brain that trigger the urge to vomit.
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Suitable age
18 years +
Max per order
1 pack
Consultation
Yes- Free Online
Most people find cyclizine starts working within about 30 minutes, with effects typically lasting 6 to 8 hours. For travel sickness, it's best taken 30 minutes to 2 hours before a journey. The usual adult dose is one tablet up to three times a day, with at least 8 hours between doses, and no more than three tablets in 24 hours.
Cyclizine is generally suitable for adults, but it isn't right for everyone. It may not be appropriate if you have certain conditions such as glaucoma, an enlarged prostate, or liver problems, or if you're taking certain other medicines. It can also cause drowsiness, so care is needed around driving or operating machinery.
Cyclizine is available through Access Doctor following a short online consultation. One of our GPhC-registered pharmacist prescribers will review your answers to check it's a suitable and safe option for you before it's dispensed. Once approved, orders are dispatched with discreet, next-day delivery available across the UK.
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| Pack sizes | 30 |
| Prescription status | Prescription Only Medicine (POM) |
| Side effects | Drowsiness, dry mouth, blurred vision, urinary retention, constipation |
| Generic available | Yes |
| Use with alcohol | Avoid — increases drowsiness |
Nausea and vomiting can arise from a number of different mechanisms in the body — from signals in the inner ear (as with vertigo and motion sickness) to chemical signals detected by the brain (as with nausea caused by opioid pain relief or cancer treatments). Cyclizine is effective across many of these causes because of how and where it acts in the body.
Cyclizine is one of the older, well-established antiemetics used in UK clinical practice. It is widely prescribed in both primary and secondary care settings, including for postoperative nausea and vomiting, palliative care, and inner ear disorders.
Cyclizine 50mg tablets are used to prevent and relieve nausea and vomiting caused by a range of conditions, including vertigo, labyrinthine disorders, motion sickness, postoperative nausea, nausea associated with narcotic analgesics, and nausea caused by radiotherapy. They are suitable for adults and children aged 6 and over.
Yes. Through Access Doctor's free online consultation, you can get cyclizine prescribed without a face-to-face GP appointment. A UK-registered prescriber reviews your answers and, if cyclizine is safe and appropriate, issues a prescription. Your medication is then dispatched — often with next-day delivery in plain, discreet packaging.
Cyclizine is typically absorbed within 30 to 60 minutes of taking a dose and its effects last around 4 to 6 hours. For motion sickness, it works best when taken 20 to 30 minutes before the start of travel. The effects may be felt more quickly in some patients depending on individual absorption.
Yes — drowsiness is one of the most common side effects of cyclizine and affects many patients. You should not drive, operate machinery, or drink alcohol while taking it. For some patients (such as those experiencing nausea at night or during palliative care), the sedative effect can be a benefit rather than a drawback.
Cyclizine should be used for the shortest time necessary to control your symptoms. If you need it for longer than a few days, speak to your GP or our clinical support team to ensure it remains the most appropriate option. Longer-term use may be appropriate in certain situations, such as palliative care, but should be supervised by a prescriber.
Cyclizine is sometimes used under medical supervision for pregnancy-related nausea and vomiting (morning sickness), particularly when first-line measures have not been effective. However, the manufacturer advises caution, especially during the first trimester, as safety data in early pregnancy is limited. Always speak to a healthcare professional before taking cyclizine if you are pregnant or breastfeeding.
Cyclizine 50mg tablets are a prescription-only medicine (POM) in the UK and cannot legally be sold without a valid prescription from a registered prescriber. At Access Doctor, our UK-registered prescribers assess your suitability as part of the free online consultation before any medication is dispensed.
Common side effects include drowsiness, dry mouth, blurred vision, constipation, and difficulty passing urine (urinary retention). Less commonly, cyclizine may cause a rapid heart rate (tachycardia), headache, or restlessness. If any side effects concern you, contact our free clinical support team or call 111.
Cyclizine works by blocking histamine and muscarinic receptors, making it particularly effective for inner ear-related nausea (such as vertigo and motion sickness) and opioid-induced nausea. Unlike domperidone and metoclopramide, it does not act on dopamine receptors and has no prokinetic effect on the stomach. This makes it a useful alternative when those medicines are contraindicated or unsuitable.
Complete Access Doctor's short, confidential online consultation — it takes around five minutes. If our UK-registered prescribers confirm cyclizine is safe and appropriate for you, a prescription is issued and your medication dispatched by our GPhC-registered pharmacy (No. 9011198), often arriving next day in plain, discreet packaging.
Cyclizine can be supplied following a short online consultation rather than a face-to-face GP visit. One of our prescribers reviews your answers to make sure it's safe and appropriate for you before it's dispensed.
Yes — cyclizine is available through registered online pharmacies like Access Doctor, subject to a brief suitability assessment. This helps make sure it's the right choice for your symptoms and doesn't interact with any other medicines you're taking.
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