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Cyclizine is an antihistamine anti-sickness medicine for nausea, vomiting and dizziness, including travel sickness and vertigo from inner-ear problems. It’s a pharmacy medicine, supplied to adults after a short online consultation with our pharmacy team.
Cyclizine can make you drowsy. Don’t drive or use machinery until you know how it affects you, and don’t drink alcohol while you’re taking it. We supply one pack of 30 tablets per order, to adults 18 and over. If you’re pregnant, speak to your GP or midwife instead. If sickness lasts more than a few days, or you can’t keep fluids down, see your GP or call NHS 111.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
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Suitable age
18 years and over
Max per order
1 pack (30 tablets)
Consultation
Yes, online consultation
Cyclizine is an antihistamine that prevents and treats nausea and vomiting. It works on the balance centre in the inner ear and the part of the brain that triggers sickness, so it’s especially useful for travel sickness, vertigo and inner-ear problems such as Ménière’s disease. It’s also used for sickness caused by strong painkillers. It isn’t the same as domperidone or prochlorperazine, which work in different ways.
The usual adult dose is one 50mg tablet up to three times a day, and no more than 3 tablets in 24 hours. For travel sickness, take it about 1 to 2 hours before you set off. It starts to work within about 30 minutes to 2 hours and lasts about 4 to 6 hours. It can make you drowsy, so don’t drive until you know how it affects you, and avoid alcohol.
Cyclizine 50mg tablets are a pharmacy medicine. Because cyclizine can be misused, we supply it only after a short online consultation, which our pharmacy team checks before anything is dispensed, and we supply one pack of 30 tablets per order. If approved before 3pm, Monday to Friday, your order is dispatched the same day in plain, discreet packaging: choose Royal Mail Tracked 48, Tracked 24 or Special Delivery guaranteed by 1pm next working day. For more on how it helps with dizziness, read our guide to cyclizine for vertigo and nausea.
| Medicine type | Antihistamine anti-sickness medicine (antiemetic) |
| Active ingredient | Cyclizine hydrochloride 50mg |
| Also known as | Valoid (brand) |
| Used for | Nausea and vomiting, including travel sickness, vertigo and Ménière’s disease |
| Dose | 1 tablet up to 3 times a day; no more than 3 tablets in 24 hours |
| Travel sickness | Take about 1 to 2 hours before setting off |
| Works in | About 30 minutes to 2 hours |
| Lasts | About 4 to 6 hours |
| Pack size | 30 tablets; 1 pack per order |
| Legal status | Pharmacy medicine (P) |
| Use with alcohol | Avoid — increases drowsiness |
| Suitable for | Adults 18 and over |
Cyclizine may be suitable if you:
• are 18 or over;
• have nausea, vomiting or dizziness from travel sickness, vertigo or an inner-ear problem, or have been told by a doctor that cyclizine suits you.
Don’t take cyclizine if you:
• are allergic to cyclizine or any of the ingredients;
• have been drinking heavily (it’s dangerous with a lot of alcohol);
• have porphyria;
• can’t tolerate lactose because of a rare inherited condition (the tablets contain lactose).
Tell us if you:
• have glaucoma, difficulty passing urine, or (in men) an enlarged prostate;
• have epilepsy, liver disease, heart failure, high blood pressure, a recent heart attack, a blockage in your stomach or bowel, or phaeochromocytoma;
• take anything that makes you sleepy, such as sleeping tablets, anxiety medicines, strong painkillers, methadone or some antidepressants;
• are breastfeeding, as cyclizine passes into breast milk.
We can’t supply cyclizine if you’re pregnant. The product information says it isn’t advised in pregnancy, so please see your GP or midwife. Our guide to cyclizine in pregnancy explains the options.
See your GP instead if you’ve been sick for more than a few days, can’t keep fluids down, have severe headache, stomach pain or blood in your vomit, or have new dizziness with weakness, slurred speech or a drooping face (call 999).
Cyclizine 50mg tablets are used to prevent and relieve nausea and vomiting from a range of causes, including vertigo and other inner-ear (labyrinthine) disorders, travel sickness, sickness after an operation, sickness caused by strong painkillers, and sickness caused by radiotherapy. We supply them to adults aged 18 and over. Our guide to cyclizine for vertigo and nausea explains more.
Yes. Cyclizine 50mg tablets are a pharmacy medicine, so you don’t need a prescription or a GP appointment. You complete a short online consultation, our pharmacy team checks that cyclizine is safe and suitable for you, and your order is dispatched in plain, discreet packaging. We supply one pack of 30 tablets per order, to adults aged 18 and over who aren’t pregnant.
It usually starts to help within 30 minutes to 2 hours, and the effect lasts about 4 to 6 hours. For travel sickness, take it about 1 to 2 hours before you set off, so it’s working by the time you travel.
It can. Drowsiness is one of the side effects people notice most, although not everyone gets it. Don’t drive, cycle or use machinery until you know how it affects you, and don’t drink alcohol while you’re taking it. For some people, such as those with sickness at night, the drowsiness can help.
Use it for the shortest time you need to control your symptoms. If you still need it after a few days, see your GP to find out what’s causing the sickness. Longer-term use, for example in palliative care, should be supervised by a doctor. If you order cyclizine often, we’ll ask you to see your GP before we supply more.
The product information says cyclizine isn’t advised in pregnancy, because there isn’t enough data on its safety. We don’t supply cyclizine if you’re pregnant. Pregnancy sickness is common and can be treated, so speak to your GP or midwife, who may prescribe an anti-sickness medicine if you need one. See our guide to cyclizine in pregnancy.
No. Cyclizine 50mg tablets are a pharmacy medicine (P), not prescription-only. A pharmacist has to check they’re suitable before supplying them, which is why we ask you to complete a short online consultation. Cyclizine injections are prescription-only and given in hospital; we don’t supply them.
Side effects people report include drowsiness, dry mouth, blurred vision, constipation, difficulty passing urine, a fast heartbeat, headache and restlessness. The product information doesn’t say how often each happens. Get help straight away if you have swelling of the face, lips or throat, difficulty breathing, yellowing of the skin or eyes, or fits. For anything else that worries you, contact our pharmacy team or call NHS 111.
Cyclizine blocks histamine and muscarinic receptors, so it works well for sickness from the inner ear (vertigo and travel sickness) and from opioid painkillers. Domperidone and metoclopramide work on dopamine receptors and help the stomach empty; cyclizine doesn’t, so it can be an alternative when they aren’t suitable. In practice: cyclizine is a pharmacy medicine and can make you drowsy; domperidone is prescription-only, isn’t used for vertigo, and is taken for no more than a week.
Complete our short, confidential online consultation; it takes around five minutes. Our pharmacy team checks that cyclizine is safe and suitable for you, and if it is, our GPhC-registered pharmacy (No. 9011198) dispenses one pack of 30 tablets. If approved before 3pm, Monday to Friday, it’s dispatched the same day in plain, discreet packaging, with next-day Special Delivery available.
Yes, from a pharmacy. Cyclizine 50mg tablets are a pharmacy medicine, so a pharmacist can supply them after checking they’re right for you, in a pharmacy or online. They aren’t on general sale in shops or on supermarket shelves. Because cyclizine can be misused, pharmacies limit how much they supply. We supply one pack of 30 tablets per order.
Yes. Cyclizine is available from registered online pharmacies like Access Doctor, after a short suitability check. The check makes sure it’s right for your symptoms and won’t interact with other medicines you take. We supply one pack of 30 tablets per order, to adults who aren’t pregnant.
One 50mg tablet up to three times a day, and no more than 3 tablets (150mg) in 24 hours. For travel sickness, take it about 1 to 2 hours before you set off.
No. Cyclizine tablets come in one strength, 50mg. The usual dose is one tablet up to three times a day; don’t take two at once unless a doctor has told you to.
No. Alcohol increases the drowsiness, and cyclizine mustn’t be taken when you’ve been drinking heavily. Avoid alcohol while you’re taking it.
Cyclizine is sometimes misused, and taking too much is dangerous, especially with alcohol or other medicines that make you sleepy. The pharmacy regulator asks online pharmacies to check every request carefully. So we supply one pack of 30 tablets per order, check previous orders, and may ask you to see your GP if you need it often.
Tell us about everything you take. Cyclizine adds to the drowsiness caused by other medicines that make you sleepy, such as sleeping tablets, anxiety medicines, strong painkillers and methadone. It can also add to the side effects of some antidepressants and other anticholinergic medicines, such as some bladder and Parkinson’s medicines.
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