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If you need urgent assistance, do not use this service. Call 111, or in an emergency call 999.
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Domperidone is a prescription-only medicine that relieves nausea and vomiting. It blocks the signals that trigger sickness and helps the stomach empty. We supply it to adults, for up to one week, after a short online consultation.
Don’t take more than 3 tablets (30mg) in 24 hours, or for more than a week. Stop taking domperidone and get medical help straight away if you have a fast or irregular heartbeat, palpitations, chest pain, fainting or fits. If sickness lasts more than a few days, or you can’t keep fluids down, see your GP or call NHS 111.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 Years +
Max per order
1 pack (30 tablets)
Consultation
Yes, online consultation
Domperidone used to be available over the counter, but in 2014 the MHRA restricted it to prescription-only supply following a European safety review. The review found a small increased risk of serious heart rhythm problems, particularly in people over 60, those taking higher doses, or those on certain other medicines. Because of this, domperidone is now only supplied after a clinician has checked it's safe for you — including reviewing your medical history and any other medications you're taking.
Take one 10mg tablet up to three times a day, 15 to 30 minutes before meals, and no more than 3 tablets in 24 hours. Treatment should usually last no longer than one week. Domperidone isn’t suitable if you have a heart condition, moderate or severe liver problems, or take certain medicines that affect heart rhythm, so our prescriber checks these first. If you’d rather not take a prescription medicine, cyclizine is a pharmacy anti-sickness tablet that works in a different way.
If domperidone may be right for you, complete our short online consultation and one of our GPhC-registered pharmacist prescribers will assess your suitability, without a face-to-face GP appointment. If it’s safe for you, a prescription is issued and dispensed by our GPhC-registered pharmacy (No. 9011198). If approved before 3pm, Monday to Friday, it’s dispatched the same day in plain, discreet packaging: choose Royal Mail Tracked 48, Tracked 24 or Special Delivery guaranteed by 1pm next working day.
| Medicine type | Prokinetic antiemetic (dopamine antagonist) |
| Active ingredient | Domperidone 10mg |
| Peak level | About 1 hour after a dose |
| Recommended use | Relief of nausea and vomiting |
| Dose | 1 tablet up to 3 times a day, 15 to 30 minutes before meals; maximum 3 tablets in 24 hours |
| Pack size | 30 tablets, £19.99 |
| Maximum duration | 1 week (per MHRA guidance) |
| Side effects | Dry mouth (common); headache, diarrhoea, breast tenderness or discharge (uncommon); rarely heart rhythm problems |
| Generic available | Yes – generic domperidone 10mg tablets contain the same active ingredient as branded Motilium |
| Regulatory guidance | MHRA Drug Safety Update (2014); domperidone SmPC |
| Legal status | Prescription Only Medicine (POM) |
Nausea and vomiting are among the most common reasons people seek medical advice in the UK. They can be triggered by a wide range of causes — including gastroenteritis, migraines, certain medications, and post-operative recovery. Domperidone is one of the most commonly prescribed anti-sickness tablets in the UK and works specifically on the parts of the body responsible for triggering the sensation of nausea.
Domperidone is sometimes known by the brand name Motilium, though generic domperidone 10mg tablets contain the same active ingredient at the same strength and are fully licensed UK medicines regulated by the MHRA. If you’re looking to buy Motilium UK or generic domperidone online, our service provides a safe, prescription-based route, with the consultation included in the price.
Domperidone 10mg tablets are used to relieve nausea and vomiting. We supply them to adults aged 18 and over. Domperidone is a prescription-only medicine, so you can’t legally buy it without a prescription; our online consultation includes the prescription if it’s right for you.
Yes. Through Access Doctor’s online consultation, you can order domperidone without a face-to-face GP appointment. A UK-registered prescriber reviews your answers and, if domperidone is safe and appropriate for you, issues a prescription. Domperidone isn’t available over the counter, so a prescription is the only legal way to buy it online in the UK.
Domperidone is absorbed quickly, reaching its highest level in the blood about an hour after a dose, and many people notice the sickness easing within that time. For the best effect, take it 15 to 30 minutes before meals.
In line with MHRA guidance, domperidone should be taken for the shortest time necessary — typically no longer than one week for the treatment of nausea and vomiting. If your symptoms continue beyond this period, please contact your GP or our clinical support team, as an alternative treatment or further investigation may be required.
Domperidone interacts with several medicines that are commonly prescribed in the UK. The most significant interactions involve CYP3A4 inhibitors (such as ketoconazole, clarithromycin, erythromycin, and certain antifungals) and QT-prolonging medicines (such as amiodarone, certain antipsychotics, and some antidepressants). Always tell your prescriber about all the medicines, supplements, and herbal remedies you are taking before starting domperidone medication.
Domperidone is considered safe for most adults when used correctly, at the lowest effective dose for the shortest possible time. It isn’t suitable if you have certain heart conditions, moderate or severe liver problems, a prolactinoma, or take specific interacting medicines. Our prescribers check all of this during your consultation.
In rare cases, high doses or prolonged use of domperidone can affect heart rhythm (QT prolongation). That’s why MHRA guidance limits use to one week and requires a prescription – another reason you should never attempt to buy domperidone from unverified sources.
Yes. Domperidone is a prescription-only medicine (POM) in the UK and cannot legally be sold without a valid prescription from a registered prescriber. Be cautious of any website offering domperidone for sale without an online consultation — this is not legal or safe practice in the UK.
The product information says domperidone should be used in pregnancy only if the benefit justifies it, and we don’t supply it if you’re pregnant. Domperidone passes into breast milk in very small amounts, and an effect on the baby’s heart can’t be ruled out. If you’re pregnant, breastfeeding or planning a pregnancy, speak to your GP or midwife.
Complete Access Doctor’s short, confidential online consultation; it takes around five minutes. If our UK-registered prescribers confirm domperidone is safe and appropriate for you, a prescription is issued and your medication dispensed by our GPhC-registered pharmacy (No. 9011198). If approved before 3pm, Monday to Friday, it’s dispatched the same day in plain packaging, by Royal Mail Tracked 48, Tracked 24 or Special Delivery guaranteed by 1pm next working day. 30 tablets cost £19.99, including the consultation and prescription.
Domperidone was moved to prescription-only status in 2014 after a safety review found a small increased risk of heart rhythm problems. A prescriber now needs to check your medical history and current medicines before it’s supplied, to make sure it’s safe for you.
Don’t take domperidone if you have a heart rhythm problem or heart disease such as heart failure, moderate or severe liver problems, low or high potassium or low magnesium, a prolactinoma, or bleeding or a blockage in your stomach or gut. It also can’t be taken with some antibiotics, antifungals and heart, mental health and HIV medicines. Our prescriber checks your medical history and medicines before it’s supplied.
Domperidone isn’t licensed to increase breast milk, and we don’t supply it for that. If you’re worried about your milk supply, speak to your midwife, health visitor, GP or an infant feeding specialist, who can help.
Motilium is the original brand of domperidone. Generic domperidone 10mg tablets contain the same medicine at the same strength and work in the same way. Since 2014, neither has been available over the counter in the UK; both need a prescription. We supply generic domperidone 10mg tablets after an online consultation, for £19.99 for 30 tablets.
We don’t supply domperidone online to people aged 65 or over. The risk of heart rhythm problems with domperidone is higher in older people, so it’s safer for your GP, who knows your full history and medicines, to decide whether it’s right for you. If you’re over 65 and being sick, see your GP or call NHS 111.
Domperidone isn’t licensed for travel sickness, and it isn’t usually used for it. Travel sickness medicines such as Kwells (hyoscine) and Avomine (promethazine) work on the balance signals from your inner ear, which is what causes motion sickness. See our travel sickness treatments.
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