I've taken these tablets for many years ( for nausea ). When I went to buy some more, as mine had expired, I was told that I could only get them from a GP ! Why ? They are very effective at reducing the sickly feeling and I shall certainly be buying more at some point.

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Domperidone Tablets
Domperidone is an antiemetic drug, which helps treat symptoms of nausea and vomiting. It can also help with symptoms of stomach cramps, heart burn and bloating by increasing the contractions within the stomach muscles and help with digestion of food.
- Relieves nausea and vomiting in adults and adolescents aged 12 years and over
- Works by blocking dopamine receptors — proven prokinetic antiemetic mechanism
- Also eases symptoms of bloating and upper abdominal discomfort
- Prescribed in line with MHRA guidance: lowest effective dose, shortest necessary duration
- Free UK online consultation — no GP appointment needed
Order before 3pm — same-day dispatch
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
No subscription required · Free repeat prescriptions · Cancel anytime
Suitability
Suitable age
18 Years +
Consultation
✓ Yes — free online
Domperidone Tablets
Domperidone is an antiemetic drug, which helps treat symptoms of nausea and vomiting. It can also help with symptoms of stomach cramps, heart burn and bloating by increasing the contractions within the stomach muscles and help with digestion of food.
Summary
| Medicine type | Prokinetic antiemetic (dopamine antagonist) |
| Active ingredient | Domperidone 10mg |
| Effective within | 30–60 minutes |
| Recommended use | Nausea and vomiting; bloating and upper abdominal discomfort |
| Pack sizes | 30 tablets |
| Prescription status | Prescription Only Medicine (POM) |
| Maximum duration | 1 week (per MHRA guidance) |
| Side effects | Headache, dry mouth, raised prolactin; rarely QT prolongation |
| Generic available | Yes |
| Regulatory guidance | MHRA Drug Safety Update (2014); domperidone SmPC |
Domperidone Tablets
About Domperidone 10mg Tablets
Nausea and vomiting are among the most common reasons people seek medical advice in the UK. They can be triggered by a wide range of causes — including gastroenteritis, migraines, certain medications, and post-operative recovery. Domperidone is one of the most commonly prescribed anti-sickness tablets in the UK and works specifically on the parts of the body responsible for triggering the sensation of nausea. Domperidone is sometimes known by the brand name Motilium, though generic domperidone 10mg tablets contain the same active ingredient at the same strength and are fully licensed UK medicines regulated by the MHRA.
FAQs
What is domperidone used for?
Domperidone 10mg tablets are used to relieve nausea and vomiting in adults and adolescents aged 12 and over who weigh at least 35kg. They may also help ease associated symptoms of bloating and upper abdominal discomfort. Domperidone is a prescription-only medicine and must be obtained following a consultation with a registered UK prescriber.
Can I buy domperidone without seeing a GP?
Yes. Through Access Doctor's free online consultation, you can get domperidone prescribed without a face-to-face GP appointment. A UK-registered prescriber reviews your answers and, if domperidone is safe and appropriate for you, issues a prescription. Your medication is then dispensed by our GPhC-registered pharmacy and dispatched — often with next-day delivery in plain packaging.
How long does domperidone take to work?
Domperidone is absorbed relatively quickly and typically begins to take effect within 30 to 60 minutes of taking a dose. For best results, it is recommended to take domperidone 15 to 30 minutes before meals.
How long can I take domperidone for?
In line with MHRA guidance, domperidone should be taken for the shortest time necessary — typically no longer than one week for the treatment of nausea and vomiting. If your symptoms continue beyond this period, please contact your GP or our clinical support team, as an alternative treatment or further investigation may be required.
Can I take domperidone with other medicines?
Domperidone interacts with several medicines that are commonly prescribed in the UK. The most significant interactions involve CYP3A4 inhibitors (such as ketoconazole, clarithromycin, erythromycin, and certain antifungals) and QT-prolonging medicines (such as amiodarone, certain antipsychotics, and some antidepressants). Always tell your prescriber about all the medicines, supplements, and herbal remedies you are taking before starting domperidone.
Is domperidone safe?
Domperidone is considered safe for most adults and adolescents aged 12 and over (weighing at least 35kg) when used correctly — at the lowest effective dose for the shortest possible time. However, it is not suitable for patients with certain heart conditions, severe liver problems, a prolactinoma, or those taking specific interacting medicines. Our prescribers assess your full suitability as part of the free consultation.
Can domperidone affect the heart?
Domperidone has been associated with a small but recognised risk of cardiac arrhythmia, including QT interval prolongation — a condition where electrical activity in the heart takes longer than normal. This risk is higher at increased doses, in older patients, and in those taking interacting medicines. Following its 2014 MHRA safety review, domperidone is only recommended at a maximum dose of 10mg up to three times daily. Our prescribers will assess your cardiac history during the consultation.
Does domperidone require a prescription in the UK?
Yes. Domperidone is a prescription-only medicine (POM) in the UK and cannot legally be sold without a valid prescription from a registered prescriber. Be cautious of any website offering domperidone without an online consultation — this is not legal or safe practice in the UK.
Can domperidone be used during pregnancy or breastfeeding?
The safety of domperidone during pregnancy has not been established and it is generally not recommended. Domperidone does pass into breast milk in small amounts; its use during breastfeeding is not routinely advised. If you are pregnant, breastfeeding, or planning a pregnancy, please speak to your GP or a registered healthcare professional before using domperidone.
How do I buy domperidone online in the UK?
Complete Access Doctor's short, confidential online consultation — it takes around five minutes. If our UK-registered prescribers confirm domperidone is safe and appropriate for you, a prescription is issued and your medication dispensed by our GPhC-registered pharmacy (No. 9011198), often arriving next day in plain, discreet packaging. All orders include a free clinical consultation and access to our pharmacist support team.
Reviews for Domperidone Tablets
Write a reviewFast and prompt service. Delivery very speedy. I would recommend highly
Five star rating easy to navigate my symptoms and have a quick and easy delivery service.
Health guides for Domperidone Tablets
Helpful articles and clinical guides related to this treatment category.
Free consultation
Online review by a UK prescriber
Next-day delivery
Order before 3pm where offered
Discreet packaging
Plain outer packaging




