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Prochlorperazine is a prescription-only medicine used to relieve nausea, vomiting, and dizziness (vertigo) in adults. It works by blocking dopamine receptors involved in triggering the sensation of sickness, and is also used to help nausea associated with migraine.
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Prochlorperazine is a phenothiazine-type medicine that has been used for many years to treat nausea, vomiting, and vertigo (dizziness), including symptoms caused by inner ear conditions such as Ménière's disease and labyrinthitis, and nausea linked to migraine.
As a prescription-only medicine, prochlorperazine is only supplied after a clinician has checked it's suitable for you — including reviewing your medical history, current health conditions, and any other medicines you're taking, since it isn't suitable for everyone.
If prochlorperazine may be right for you, our free online consultation lets one of our GPhC-registered pharmacist prescribers assess your suitability without needing a face-to-face GP appointment. If it's appropriate and safe, a prescription is issued and your medication is dispatched with discreet delivery across the UK.
| Medicine type | Antiemetic (phenothiazine, dopamine antagonist) |
| Active ingredient | Prochlorperazine 5mg |
| Effective within | 30-40 minutes |
| Recommended use | Nausea, vomiting and vertigo; migraine-associated nausea |
| Pack sizes | 30 tablets |
| Prescription status | Prescription Only Medicine (POM) |
| Maximum duration | As advised by your prescriber — usually short-term |
| Side effects | Drowsiness, dizziness, dry mouth; rarely movement disorders (extrapyramidal symptoms) |
| Generic available | Yes — prochlorperazine is the generic name (brand: Stemetil) |
| Regulatory guidance | MHRA-licensed medicine; see patient information leaflet |
Nausea and vomiting are among the most common reasons people seek medical advice in the UK, and can also occur alongside vertigo (a spinning or dizzy sensation) caused by conditions such as Ménière's disease and labyrinthitis. Prochlorperazine is a long-established anti-sickness medicine that works on the parts of the brain and inner ear responsible for triggering these symptoms.
Prochlorperazine is sometimes known by the brand name Stemetil, though generic prochlorperazine 5mg tablets contain the same active ingredient at the same strength and are fully licensed UK medicines regulated by the MHRA.
Prochlorperazine is used to treat nausea, vomiting, and vertigo (dizziness), including symptoms caused by inner ear conditions such as Ménière's disease and labyrinthitis, and nausea associated with migraine.
Yes. Our free online consultation is reviewed by a UK-registered prescriber, so you don't need a face-to-face GP appointment. If prochlorperazine is suitable for you, a prescription is issued and your medication is dispatched by our GPhC-registered pharmacy.
Oral prochlorperazine tablets typically start to work within 30 to 40 minutes.
Prochlorperazine is usually prescribed for short-term use, at the lowest effective dose. Your prescriber will advise how long you should take it based on your symptoms.
Prochlorperazine can interact with certain other medicines, including those that affect the central nervous system, heart rhythm, or blood pressure. Always tell your prescriber about any other medicines you're taking so they can check for interactions.
Prochlorperazine is a licensed UK medicine that's generally safe when taken as prescribed. Like all medicines it can cause side effects, and it isn't suitable for everyone — our prescribers assess your medical history before issuing a prescription.
Prochlorperazine isn't routinely recommended during pregnancy or breastfeeding unless specifically advised by a doctor. Speak to your prescriber or GP if you're pregnant, breastfeeding, or trying to conceive.
Complete our short online consultation, and if a UK-registered prescriber determines prochlorperazine is suitable for you, a prescription will be issued and your medication dispatched with discreet delivery.
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