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If you need urgent assistance, do not use this service. Call 111, or in an emergency call 999.
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An anti-inflammatory painkiller for migraine attacks, often taken with a triptan. For adults aged 18 to 65 with diagnosed migraine, after an online consultation with a GPhC-registered pharmacist prescriber.
For adults aged 18 to 65 whose migraine has been diagnosed by a doctor. Not for pregnancy or breastfeeding, or if you’ve had a stomach ulcer or bleed, or a reaction to aspirin or another anti-inflammatory. Tell us every medicine you take.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 to 65 years
Max per order
1 pack (28 tablets)
Consultation
Yes, online consultation
Naproxen is an anti-inflammatory painkiller (an NSAID). It’s licensed for pain and inflammation, such as arthritis, gout and period pain. UK guidance (NICE) recommends taking an anti-inflammatory like naproxen together with a triptan for migraine attacks, because the combination often works better than either alone. Using naproxen for migraine is “off-label”, which means it’s outside its product licence; the prescriber will check it’s right for you.
On its own, naproxen helps fewer people than a triptan, so it’s mainly used alongside one, such as sumatriptan or rizatriptan. Our naproxen for migraine guide explains how to take them together. See all our migraine treatments. If you take naproxen for joint pain or gout, see naproxen tablets instead.
| Active ingredient | Naproxen 500mg |
| Type | Anti-inflammatory painkiller (NSAID) |
| Dose | One tablet at the start of an attack, with food |
| Prescription status | Prescription-only medicine, used off-label for migraine, supplied after an online consultation |
| Suitable for | Adults 18 to 65 with diagnosed migraine |
| Price | 28 tablets £19.99 |
Who we can supply: adults aged 18 to 65 whose migraine has been diagnosed by a doctor, and who agree to us sharing the consultation with their GP.
This service isn’t suitable if you:
are pregnant, trying for a baby or breastfeeding (please speak to your GP or midwife)
have had a stomach ulcer or bleeding, or a bleed or perforation after taking an anti-inflammatory
have had asthma, a rash or swelling after taking aspirin, ibuprofen or another anti-inflammatory
have severe heart, kidney or liver problems
have headaches that are new, have changed, or haven’t been diagnosed as migraine
use painkillers on 15 or more days a month, or triptans on 10 or more days (see medication overuse headache)
The prescriber will also check whether naproxen is safe for you if you have asthma, high blood pressure, heart disease, a previous stroke, or Crohn’s disease or ulcerative colitis.
Tell the prescriber about every medicine you take. Don’t take naproxen with other anti-inflammatories such as ibuprofen, diclofenac or aspirin for pain. It needs checking with blood thinners (such as warfarin, apixaban or clopidogrel), low-dose aspirin, SSRI antidepressants, steroids, lithium, methotrexate, blood pressure medicines and water tablets (diuretics), ciclosporin and tacrolimus.
It can help, especially taken with a triptan. NICE recommends combining a triptan with an anti-inflammatory such as naproxen, because together they often work better than either alone. On its own, naproxen helps fewer people than a triptan. See our triptans guide.
No. Naproxen is licensed for pain and inflammation, such as arthritis, gout and period pain, but not specifically for migraine. Using it for migraine is “off-label”. NICE guidance supports anti-inflammatories for migraine attacks, and the prescriber will only supply it if it’s right for you.
Yes. You can take one naproxen 500mg tablet at the same time as your usual triptan, such as sumatriptan. Don’t take naproxen with another anti-inflammatory, such as ibuprofen or aspirin for pain.
Take one tablet at the start of an attack, and one more after 6 to 8 hours if the headache comes back. Don’t take more than 2 tablets in 24 hours. If you need painkillers or triptans on 10 or more days a month, see your GP, because using them that often can cause medication overuse headache.
We don’t supply naproxen online if you’re pregnant, trying for a baby or breastfeeding. Naproxen mustn’t be used in the last 3 months of pregnancy, and should be avoided from 20 weeks unless a doctor advises it. Please speak to your GP or midwife; paracetamol is usually tried first in pregnancy.
It’s the same medicine. This listing is for migraine, after a migraine consultation. If you need naproxen for joint pain or gout, see naproxen tablets.
Helpful articles and clinical guides related to this treatment category.
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Online review by a UK prescriber
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Order before 3pm where offered
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