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Imigran Nasal Spray contains sumatriptan, the most widely used triptan, in a single-use spray. It’s useful if you feel sick or vomit early in a migraine attack, because you don’t need to swallow a tablet. For adults aged 18 to 65 with diagnosed migraine, after an online consultation with a GPhC-registered pharmacist independent prescriber.
For adults aged 18 to 65 whose migraine has been diagnosed by a doctor, for the nasal spray and strength you already use. If you have heart disease, uncontrolled high blood pressure or a new or different headache, please see your GP.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 to 65 years
Max per order
2 packs
Consultation
Yes, online consultation
Imigran Nasal Spray contains sumatriptan, a triptan that treats migraine attacks. Each device is a single dose: you spray it once into one nostril. Because you don’t swallow it, it can help when nausea or vomiting make tablets hard to take. Our sumatriptan guide explains how sumatriptan works.
Sumatriptan also comes as tablets; your GP can advise if a different form would suit you better. Our triptans guide compares the options, and you can see all our migraine treatments.
| Medicine type | Triptan (5-HT1B/1D agonist) |
| Active ingredient | Sumatriptan 10mg or 20mg per single-use spray |
| Dose | One spray into one nostril as the headache starts (adults usually 20mg); a second dose after at least 2 hours if it returns; no more than 2 sprays (40mg) in 24 hours |
| Prescription status | Prescription-only medicine (POM) |
| Suitable for | Adults 18 to 65 with diagnosed migraine |
| Price | 10mg or 20mg: 2 sprays £24.99 · 4 sprays £47.99 · 6 sprays £61.99 |
| UK guidance | NICE CG150; Imigran Nasal Spray SmPC |
Who we can supply: adults aged 18 to 65 whose migraine has been diagnosed by a doctor, for the same triptan, strength and form you already use. If your migraine is diagnosed and you’ve so far used painkillers, a prescriber can consider a first triptan. We share the consultation with your GP. We can’t switch you to a different triptan or form online; your GP can.
How many: up to 2 packs per order. If you use triptans on 10 or more days a month, we’ll ask you to see your GP, because that can cause medication overuse headache and you may need preventive treatment.
This service isn’t suitable if you:
haven’t been diagnosed with migraine, or your headaches are new, different or getting worse
have had a heart attack, angina, a stroke or mini-stroke (TIA), or have circulation problems in your legs
have high blood pressure that isn’t controlled
get weakness on one side of the body with your migraines (hemiplegic migraine)
have severe liver disease
are under 18 or over 65
are pregnant, trying for a baby or breastfeeding (please speak to your GP or midwife first)
Tell the prescriber if you:
have heart disease risk factors, such as diabetes, high cholesterol, smoking, a family history of early heart disease, or you’re a man over 40 or a woman past the menopause
take an antidepressant (SSRIs such as sertraline or citalopram, SNRIs such as venlafaxine, or an MAOI) or St John’s wort, which raise the risk of serotonin syndrome
take another triptan or an ergotamine medicine
have liver or kidney problems
use the combined contraceptive pill and get migraine with aura (see our migraine and the pill guide)
Imigran Nasal Spray contains sumatriptan, a triptan that treats migraine attacks once they’ve started, with or without aura. It doesn’t prevent migraines.
Blow your nose, close one nostril, put the tip in the other, breathe out through your mouth, then breathe in gently through your nose as you press the plunger firmly once. Keep your head upright for 10 to 20 seconds. Each device is a single dose, so don’t test it first.
It can start to work a little sooner than a tablet for some people, and it doesn’t depend on your stomach, which slows down during a migraine. The main benefit is that you don’t need to swallow anything.
Some of the spray runs down the back of the throat, and sumatriptan tastes bitter. An unpleasant taste is very common. Breathing in gently rather than sniffing hard can help.
The strength you’re already prescribed. Most adults use 20mg. If it works and the migraine returns, you can use a second spray after at least 2 hours. Don’t use more than 2 sprays (40mg) in 24 hours.
No. We supply the same triptan, strength and form you already use. If Imigran Nasal Spray isn’t working well, or you’d like to try a different form such as tablets or a wafer, please speak to your GP, who can review your treatment with your full history. Our triptans guide explains how the triptans differ.
Use triptans on fewer than 10 days a month. Taking them more often than that, for 3 months or more, can make headaches more frequent; this is called medication overuse headache. If you need Imigran Nasal Spray that often, see your GP about preventive treatment rather than ordering more. See our chronic migraine guide.
Yes. NICE recommends a triptan combined with an anti-inflammatory painkiller such as naproxen or ibuprofen, or with paracetamol, and the combination often works better than a triptan alone. Don’t take two anti-inflammatories together, and take them with food.
Triptans aren’t ruled out, but we don’t supply them online in pregnancy or while breastfeeding, so please speak to your GP or midwife. NICE advises paracetamol first in pregnancy, with a triptan considered after discussing the risks; sumatriptan has the most safety information. If you’re breastfeeding, the Imigran leaflet advises not breastfeeding for 12 hours after a dose.
See your GP if your headaches change, become more frequent, or you need treatment on 10 or more days a month. Get urgent help (call 999) if you have a sudden, severe “thunderclap” headache, a headache with weakness, numbness, a drooping face or slurred speech, a headache with fever, a stiff neck or a rash, or a headache after a head injury. These aren’t migraine and need assessment straight away.
Helpful articles and clinical guides related to this treatment category.
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