Replens MD Vaginal Moisturiser

Replens MD is a non-hormonal vaginal moisturiser used to relieve persistent vaginal dryness. Its active ingredient, polycarbophil, is a bioadhesive polymer that clings to the vaginal wall and gradually releases moisture into the tissue over two to three days. It also helps restore vaginal pH closer to its natural premenopausal level, which can ease soreness, itching, and discomfort during everyday activities and sex.

Lubricants are short-acting and used in the moment, mainly to reduce friction during sex. Replens is a longer-acting moisturiser — it's designed to be used regularly, whether or not you're sexually active, to keep the vaginal tissues hydrated day-to-day. Many people use the two together: Replens for ongoing comfort, and a separate lubricant during intercourse if needed.

The standard regimen is one applicator inserted into the vagina every three days, so roughly two to three times a week. Each dose continues to work for around 72 hours, so daily use isn't necessary and could cause irritation.

Each prefilled applicator is single-use. You insert it into the vagina much like a tampon, press the plunger to release the gel, then dispose of the applicator. Bedtime is usually recommended so the product has time to settle without leaking onto underwear.

No. Replens MD is hormone-free, which is one of the reasons it's often recommended for women who can't or don't want to use oestrogen — for example, those who have had certain hormone-sensitive cancers, or anyone who simply prefers a non-hormonal option.

Replens is widely used in this group precisely because it contains no oestrogen and acts only locally. That said, anyone with a history of breast cancer should always check in with their oncology team before starting any new vaginal product — even a non-hormonal one — so the decision can be tailored to their specific situation.

Many users notice an improvement in dryness and comfort within the first one to two weeks, but it can take up to a month of consistent use for the full effect to be felt. Vaginal tissue rehydration is gradual, not instant.

Yes. Replens itself is not a lubricant for intercourse, but it doesn't interfere with sex. Most people apply it well before bed or several hours before any planned sexual activity, and use a separate water-based or silicone lubricant during sex if extra glide is needed.

Replens is generally compatible with latex condoms, but always check the leaflet that comes with your specific batch. If in doubt, use a fresh water-based lubricant alongside, as silicone and oil-based products can degrade latex.

Most users tolerate it well. Some experience mild irritation, itching, or a small amount of clumpy white discharge as the used gel works its way out — this is normal and not a sign of infection. If you develop persistent burning, unusual bleeding, or an offensive-smelling discharge, stop using it and speak to a clinician to rule out infection.