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Seretide Accuhaler is a twice-daily purple preventer inhaler that combines a steroid and a long-acting bronchodilator, for asthma or COPD. For adults already prescribed it.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Secure & confidential · Reviewed by a UK prescriber
Suitable age
18 years and over
Max per order
2 Accuhalers
Consultation
Yes, for people already prescribed it
Seretide Accuhaler is a purple combination preventer inhaler made by GSK. Each dose contains fluticasone propionate, an inhaled steroid that calms inflammation in the airways, and salmeterol 50 micrograms, a long-acting bronchodilator that keeps the airways open for about 12 hours. Because both are in one inhaler, the bronchodilator is never taken without the steroid.
It comes in three strengths: 100/50, 250/50 and 500/50 (micrograms of fluticasone/salmeterol per dose). All three are licensed for asthma; only the 500/50 is licensed for COPD. The usual dose is 1 inhalation twice a day. The Accuhaler is a dry powder inhaler: you load a dose with the lever and breathe in quickly and deeply, so there’s no need to time a press with your breath.
Seretide doesn’t relieve sudden symptoms, so always keep a blue reliever. We supply Seretide Accuhaler as a repeat, at the same strength, for adults already prescribed it. Our preventer inhaler guide explains how preventers and combination inhalers work.
| Active ingredients | Fluticasone propionate + salmeterol |
| Available strengths | 100/50, 250/50 and 500/50 mcg |
| Device type | Accuhaler (dry powder inhaler), with dose counter |
| Usual dosing | One inhalation twice daily (morning and evening) |
| Doses per inhaler | 60 (about a month) |
| Legal category | Prescription-only medicine (POM) |
| Used for | Asthma (all strengths); COPD (500/50 only) |
Take 1 inhalation in the morning and 1 in the evening, every day, even when you feel well. It works by preventing inflammation over time, not by relieving symptoms in the moment.
Open the Accuhaler by pushing the thumb grip until it clicks. Slide the lever away from you until it clicks: this loads a dose. Don’t tip it or close it now.
Breathe out gently, away from the mouthpiece. Seal your lips around the mouthpiece and breathe in quickly and deeply. Hold your breath for about 10 seconds, then breathe out slowly. Close the Accuhaler.
Rinse your mouth with water and spit it out after each dose, to reduce the risk of oral thrush and a hoarse voice.
The dose counter shows how many doses are left. Order a new one before it reaches zero.
Seretide Accuhaler is a combination preventer inhaler containing fluticasone propionate (an inhaled steroid) and salmeterol (a long-acting bronchodilator). It’s used every day to keep asthma or COPD under control: the steroid calms airway inflammation and the salmeterol keeps the airways open for about 12 hours. It doesn’t give immediate relief.
Fluticasone calms the inflammation in the airways; salmeterol relaxes the airway muscles for about 12 hours. Having both in one inhaler means the long-acting bronchodilator is never taken without the steroid, which is safer in asthma than using salmeterol alone, as with Serevent.
You should order the strength you’ve already been prescribed. All three are for asthma, from the lowest steroid dose (100/50) to the highest (500/50); only the 500/50 is licensed for COPD. We don’t change strengths
Yes, if you’re 18 or over and already prescribed Seretide Accuhaler. Complete a short consultation and a UK pharmacist prescriber reviews it. Prices for 1 Accuhaler: 100/50 £48.99, 250/50 £77.99, 500/50 £87.99 (up to 2 per order). Approved before 3pm, Monday to Friday? Dispatched the same day by Royal Mail Tracked 48, Tracked 24 or Special Delivery guaranteed by 1pm next working day.
The salmeterol effect builds over the first few doses; the full anti-inflammatory effect of fluticasone develops over a few weeks. Keep using it every day.
Rinsing your mouth with water and spitting it out clears away steroid left in your mouth and throat. Without this, you’re more likely to get oral thrush or a hoarse voice.
Headache, hoarse voice, oral thrush, throat irritation and muscle cramps are the most common. Rinsing your mouth after each dose reduces the throat effects. In COPD, Seretide raises the risk of pneumonia, so report a fever or changes in your phlegm.
The Accuhaler is a dry powder inhaler you breathe in quickly from; the Seretide Evohaler is an aerosol you press as you breathe in slowly, usually with a spacer. We supply the Accuhaler. Symbicort combines a different steroid with formoterol, which acts within minutes, so it can also be used as a reliever on some plans; Seretide is maintenance only.
Switching between combination inhalers isn’t a like-for-like swap: steroid doses, devices and how the inhaler is used all differ. A prescriber should plan the switch and review your asthma a few weeks later. We only supply Seretide as a repeat at your current strength.
Helpful articles and clinical guides related to this treatment category.
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