Spedra tablets contain the active ingredient Avanafil.

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What is Spedra?

Spedra is the brand name for the active ingredient avanafil and is used to treat impotence. It works in the same way as the traditional anti-impotence medications such as Sildenafil (Viagra) and Tadafil (Cialis).

Key benefits of Spedra

Spedra is shown to be effective within only 15minutes of taking the pill.

Can be used by men who are sensitive to alternative ED medications such as Sildenafil (Viagra) or Tadalafil (Cialis).

Some ED medications can cause visual or hearing disturbances, the incidence of these symptoms are very low with Spedra.

How does Spedra work?

Spedra is the brand name for the active ingredient called avanafil. Avanafil works by inhibiting an enzyme known as PDE-5 (phosphodiesterase type 5), this dilates blood vessels within the penis allowing more blood flow.  Increasing blood flow to the penis allows a man to gain and sustain an erection when suitably aroused. Spedra is fast-acting and it only takes 20minutes for it to start working.

How to take Spedra

Spedra tablets comes in three dosages: 50mg, 100mg, 200mg.

It is recommended to start your treatment on 100mg, this is then altered if need be depending on your response. Please contact us regarding dosage advice.

  • 50mg – For men who have experienced some side effects
  • 100mg – Recommended starting dose
  • 200mg – This can be titrated up from the starting dose of 100mg if if the 100mg dose was ineffective

Precautions and Side-effects


Most men who require Spedra are suitable for it.

It is important to note that certain medications can prohibit you from taking Spedra, Any medications you take that include nitroglycerin, isosorbide mononitrate, amyl nitrate (poppers) or nitrate medications to treat chest pain, in such instances, Spedra is not suitable for you.

If you suffer from kidney problems or liver problems you will require special assistance with dosages and may not even be suitable for this treatment. Please contact our customer support team.

If you are allergic to the active ingredient avanafil it can be dangerous for you to use this treatment.

Avoid drinking grapefruit juice prior to taking your avanafil dosage.


For further information about erectile dysfunction treatments, please refer to the NHS website, as well as the Spedra (avanafil) patient leaflet available to download from below.

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