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An antibiotic gel (clindamycin 1%, with zinc) applied once a day to treat red, inflamed acne spots. It’s always used with a benzoyl peroxide or retinoid treatment.
Order before 3pm — same-day dispatch (MON - FRI)
~5 min consultation
Suitable age
18 years +
Max per order
2 × 30g tubes (12 weeks)
Consultation
Yes, with a review at 12 weeks
Zindaclin is a prescription-only gel containing clindamycin 1% (as clindamycin phosphate), an antibiotic, in a gel base that also contains zinc. It’s licensed for mild to moderate acne. Clindamycin reduces the acne bacteria (Cutibacterium acnes), which helps red and pus-filled spots settle. It’s applied just once a day.
NICE advises against using an antibiotic on the skin on its own, because acne bacteria can become resistant. So we supply Zindaclin together with a benzoyl peroxide treatment such as Acnecide or a retinoid such as Differin. If you’d rather use one product, Duac and Treclin combine clindamycin with a second treatment in a single gel. For every option, see our acne treatments.
| Active ingredient | Clindamycin 1% (as clindamycin phosphate), in a gel containing zinc acetate |
| Type | Antibiotic gel for the skin |
| Used for | Mild to moderate acne, with benzoyl peroxide or a retinoid |
| How to use | A thin layer once a day |
| Course | Up to 12 weeks, then a review |
| Prescription status | Prescription-only medicine (POM) |
Acne spots form when pores block with oil and dead skin and bacteria (Cutibacterium acnes) grow inside them, causing redness and swelling. Clindamycin stops these bacteria growing, which helps the spots settle. It doesn’t unblock pores, which is one reason it’s paired with benzoyl peroxide or a retinoid, which do.
Zindaclin is a prescription gel used to treat mild to moderate acne. It contains the antibiotic clindamycin 1%, which reduces the bacteria linked to acne, helping red and pus-filled spots settle. It’s always used with a benzoyl peroxide or retinoid treatment, because an antibiotic used on the skin on its own can let bacteria become resistant.
Apply a thin layer once a day to the whole affected area, after washing as normal, rinsing well and patting your skin dry. Avoid your eyes, mouth and the inside of your nose. Use your benzoyl peroxide or retinoid treatment as your prescriber advises.
NICE advises that antibiotics applied to the skin shouldn’t be used on their own, because acne bacteria can become resistant to them. So benzoyl peroxide (such as Acnecide) or a retinoid (such as Differin) is always used alongside it. These also unblock pores, which Zindaclin doesn’t do. If you’d prefer one product, Duac combines clindamycin and benzoyl peroxide in a single gel.
The product information says it can take 4 to 6 weeks to see a response, so keep using it every day. Your prescriber will review you at 12 weeks: if your skin is clear, you’ll usually carry on with a treatment without an antibiotic to keep it clear. If it hasn’t helped, we’ll suggest another option.
About 1 in 10 people get some skin irritation. Common side effects include dryness, redness, burning, itching, irritation around the eyes, and worsening of acne. Less commonly, the skin can become painful or scaly. If you get diarrhoea while using Zindaclin, stop using it and get medical advice.
There’s limited information about using Zindaclin during pregnancy, and it isn’t known whether clindamycin passes into breast milk after use on the skin. We don’t supply acne treatment online if you’re pregnant, trying for a baby or breastfeeding: please speak to your GP, who can advise on the safest options.
No. Zindaclin only comes as a 1% gel. If you’re looking for a clindamycin lotion, which can be easier to spread over the back and chest, Dalacin T contains the same antibiotic.
No. Zindaclin is a prescription-only medicine, so pharmacies such as Boots can only supply it with a prescription. You can get a prescription from Access Doctor after an online consultation with one of our pharmacist prescribers.
Yes, Zindaclin is prescription-only, so you can’t buy it over the counter. You can get it from Access Doctor after a short online consultation: you answer questions about your skin, health and previous treatments, a pharmacist prescriber checks it’s suitable for you, and if it’s approved we dispatch it from our UK pharmacy, together with your benzoyl peroxide or retinoid treatment. We supply up to 12 weeks at a time.
Apply twice a day
FOR EXTERNAL USE ONLY.
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